United States Department of Agriculture, Agriculture Research Service intends to award the following as a sole source procurement award to the following vendor: Creative Biogene, Inc. located at the following address - 4501 Ramsay Road, Shirley, New York, 11967-4715
Creative Biogene, Inc. is the only known vendor who can provide the following USDA STATEMENT OF WORK FOR METABOLOMICS SERVICE - The platform Creative Biogene, Inc. is using includes a unique data pipeline for feature extraction and preprocessing that enable for rare or very low abundance metabolites to be identified, especially for those of gut microbe origin and derived from xenobiotics metabolism.
Project objective. The objective of this service is to identify and quantify hundreds of metabolites found in either serum or gut contents - feces - of pigs and other experimental animals.
Scope of work. The project involves sample preparation for serum or feces or gut contents from - 20 groups of animals with 5 to 10 samples per group. These samples will be sent to the Contractor to perform untargeted or global metabolite identification and quantification.
The Government responsibilities shall include providing the following:
1) USDA will be responsible for shipping these samples in sufficient dry ice using an overnight express service in 3 batches to the Contractor;
2) USDA will cover the cost for shipping and returning the samples;
Detailed Technical Requirements (Contractor Requirements).
The Contractor shall:
1) Identify, quantify, and analyze 150 serum or fecal samples of pigs and other animals.
2) Prepare a final Analysis Report with

A: a detailed list of reagents used (purity and maker);
B: detailed procedures used for sample preparation;
C: model and makers of all instruments used for LC-MS Analysis;
D: detailed MS parameter settings; and
E: data acquisition, feature extraction and pre-processing procedures and parameters
3). Provide with an excel spreadsheet containing the following information:
Name of metabolites detected;
CAS number of the metabolites
relative quantitation;
Metabolites of gut microbial origin
Other relevant results (such as statistical testing).
Deliverables.
The Contractor shall provide a final Analysis Report and a final excel spreadsheet reporting the parameters identified above and or a summary report highlighting metabolites that display significant statistical differences between the groups of interest.
Period of performance. May 1, 2019 to April 30, 2020.
The Small Business size standard threshold is 1,000 employees - for North American Industrial Classification Code 541714 and this requirement will be reserved exclusively for small busineses.
Vendors who believe they can provide the above are invited to submit substantiating documentation by no later than April 23, 2019 to [email protected]. No late vendor quotes or vendor questions shall be accepted. The anticipated award date is April 24, 2019. The low quote vendor that can provide all of the above specifications must mandatorily have their companies Dun and Bradstreet Number registered as current and active by no later than April 23, 2019 at the web site: www.sam.gov at toll free phone no. 1-866-606-8220

Bid Protests Not Available