This solicitation number is RFQ2358677 and the solicitation is issued as a Request for Quotation (RFQ). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-54.

The National Institute on Drug Abuse (NIDA) on behalf of the National Institute of Neurological Disorders and Stroke (NINDS) has a requirement for an ultracentrifuge which includes a rotor package and tubes (1/2X2 ¼ (13X56) PA TW Box 50 and 1/2X2 ¼ (13X56) PC TW Box 50). The ultracentrifuge must have the following components:

(1) Biosafety: The ultracentrifuge and the rotor has to be Biosafety certified. If necessary (e.g. for centrifugation of infectious agents), the ultracentrifuge has to fit inside a standard biosafety hood.

(2) Flexibility: The ultracentrifuge and the rotor must be able to spin flexible volumes of fluids ranging from ~4.55cc, 2-3cc and down to 1.5cc for at least 8 different patient samples at the same time. In addition, it must also offer flexibility in acceleration and deceleration and timing programs that are necessary for reproducible separations.

(3) Versatility & Ease of Utilization of Tubes: NINDS's application will require utilization of both polyallomer and polycarbonate tubes as well as closed (sealed) systems that do not require utilization of extra devices as wrench or crimping tool or heating system.

(4) High Spinning Speed: The system must have spinning forces up to 500,000g.

(5) Reliability: The ultracentrifuge must be able to restart and continue the program and allow manual access to samples in case of power interruption or electronic failure. The technical support should be available within the same day when a problem occurs and within 24 hours to assure uninterrupted utilization required for clinical trial work.

(6) Compliance with 21 CFR 11 for FDA monitoring of clinical trials: The ultracentrifuge must have remote control monitoring and user programmable software that includes password protection, rotor logging, 21 CFR Part 11 compliance and data export.

Offerors will be evaluated on their ability to meet technical specifications. Offers will also be evaluated on best value in relation to price. Quotations are to be sent electronically to Korriise LaRoche, Contract Specialist at [email protected].

Offerors must include a completed copy of the provision at 52.212-3, Offeror Representations and Certifications Commercial Items, with its offer. Clause at 52.212-4, Contract Terms and Condition Commercial Items, applies to this acquisition. Clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items, applies to this acquisition.