Description:
RECOVERY - This is a Sources Sought notice; this is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This procurement will be firm-fixed price and is funded in whole by the American Recovery and Reinvestment Act [ARRA] of 2009 and is subject to the reporting requirements of the Act. The North American Industry Classification System (NAICS) code for this procurement is 334516 and the small business size is 500 employees. SCHEDULE: The National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rocky Mountain Laboratories has a need to sequence new and re-emergent pathogens and human patient genomes to determine the genetic mutations responsible for their immunological disorders and to perform research on the Novel Influenza A (H1N1) virus of swine origin. The laboratory currently has several DNA Sequencing systems, each with its own unique capabilities. This additional piece of genetic analysis equipment is necessary to meet the increased workload of this new research project.

Many NIAID DIR projects proposed to the RML focus on small, targeted patient cohorts where current operational technologies such as the Affymetrix 1.5 million human SNP chip or human transcriptome array are limited by the lack of suitable numbers of ethnicity-matched patients and controls. The RML currently uses several DNA sequencing systems; i.e. Roche 454, Applied Biosystems SOLiD, and the Illumina Genome Analyzer II (GAII). Each machine provides a unique platform and technology for performing Next Generation DNA and/or RNA sequencing; however the significant increase in sequencing depth required for analyzing at a genome level; single patient samples, knock-out mice or other rare samples, where biological replicates are not available requires that a cost-effective, high throughput, human and pathogen genome sequencer be procured.

Interested firms that believe they have the capabilities necessary to accomplish this project shall provide the following information: Company Name, DUNS Number, Address, Point of Contact, e-mail address, and business size. Respondents may submit their capability statements and all other requested information not later than 4:30 PM (MDST) 08/XX/2010 describing their capability to meet these requirements. Please reference the solicitation number on all related correspondence. This information may be mailed or faxed to the POC indicated above (Fax - 406-363-9288). All Contractors must agree to the ARRA Reporting Requirements.

"Disclaimer and Important Notes. This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualification to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a combined synopsis/solicitation may be published in Federal Business Opportunities. However responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation."

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