NanoString is the only company to sell this type of kit. The system utilizes a novel digital technology that is based on direct multiplexed measurement of gene expression and offers high levels of precision and sensitivity (<1 copy per cell). The technology uses molecular barcodes and single molecule imaging to detect and count hundreds of unique transcripts in a single reaction. The NIAAA lab experiments rely on the ability to detect small changes in the expression of multiple mRNA, from low amounts of tissue available when specific brain nuclei are dissected. From published data and preliminary experiments with another NIH core facility, Nanostring technology is a unique, proprietary and patented tool to analyzing gene expression with the precision, sensitivity and linearity require for these experiments. There is no comparable, commercially available technology. This is set aside for Small Businesses.

In compliance with Federal Acquisition Regulation (FAR) 13.106-1(b) Soliciting from a single source. This notice of intent is not a request for competitive proposals, however; all responses received, before the closing date, of this announcement will be considered by the Government. A determination by the Government not to compete this proposed acquisition is based upon responses to this notice and is solely within the discretion of the Government. It is anticipated that the RFQ NIH-NICHD-15-003 will be available fifteen (15) days after the publication date of this synopsis. Receipt of quotations will be due ten (10) days after the release of the RFQ. All interested parties to this solicitation may request a copy of the RFQ package in writing to the attention of Ms. Patricia Haun at Eunice Kennedy Shriver National Institute Child Health and Human Development (NICHD), 6100 Executive Blvd., Room 5C01, Rockville, MD 20852 or via email [email protected]. All requests must contain offerors name, address, telephone number and fax number. Email addresses are encouraged but not mandatory
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