This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6, simplified acquisition procedures and the resultant purchase order will include all applicable provisions and clauses in effect through the Federal Acquisition Circular 05-35. This announcement constitutes the only 100% total small business set aside solicitation and a written solicitation will not be issued. This synopsis, NAICS code 423450, is to notify contractors that the government intends to issue a Firm Fixed Price Purchase Order in accordance with FAR Part 13.106 for the following statement of work, under the simplified acquisition procedures. Any firm that believes it is capable of providing the required service as stated herein may submit a capability statement to document its ability to provide the required services. A determination to compete this procurement based on a response to this notice is solely within the discretion of the Government. Award will be made to the party whose quote offers the best value to the Government. The Government may award this contract to other than the lowest price technically acceptable quote. The Government will evaluate information based on the following evaluation criteria: Technical Capability and Price. Technical Capability is significantly more important than price. This solicitation is issued as a Request for Quotation (RFQ). The Food and Drug Administration (FDA) intends to award a purchase order for a microplate reader. General Duties/Description of Work Brand Name or Equal. - Tecan Infinite M1000 Quadruple Monochromator Microplate Reader - Basic Instrument including packaging (part#30034301) - Power Cable (part#13360002) - Absorbance option (part#30034190) - Excitation Monochromator option (part#30033503) - Emission Monochromator option (part#30034207) - Fluorescence, Top Read option (part#30034121) - Fluorescence, Bottom Read option (part#3003673) - Fluorescence Polarization option (part#30034127) - Luminescence with Dual Color (part#30034298) - First Injector (part#30034835) 500 ul - Second Injector (part#30035599) 1,000 ul - Shipping and Handling A. Detection Modes: Absorbance (Abs) / Fluorescence Intensity (FI) / TR Fluorescence (TRF) / Fluorescence Polarization (FP) / Luminescence; Plate Formats: 6, 12, 24, 48, 96, 384 and 1536 well plates B. Absorbance (tunable): Wavelength Range: 230 – 1000 (UV to NIR) C. Fluorescence(tunable): QUAD MONOCHROMATORS: (1nm steps)stray light 2 x 10-7: 2-Excitation and 2-Emmission monochrometers (NO CUTOFF FILTERS) a. Wavelength Range: 230nm – 850nm b. 3-D Fluorescence Scan for fluorophore characterization D. Fluorescence Polarization: Excitation – LED –Based: 4 LEDs: 470, 530, 590, 635 Emission Tunable E. Autofocus using ‘Z-plate height’ optimization Internal Auto Spectral Correction F. Variable Bandwidth Selection: 2 - 20nm bandwidths in 1nm steps G. Flash & glow luminescence read in 96, 384 and 1536 well plates; Single Photon Counting PMT Up to 2 injectors: syringe sizes 500 ul, 1000 ul or 2,500 ul H. Fully MODULAR monochromator-based microplate detection system for absorbance, fluorescence (top, bottom, excitation, emission), luminescence time-resolved fluorescence and fluorescence polarization, barcode reader left or right side and front mounted integrated stacker I. Detectors Photomultiplier Tube (PMT) for fluorescence measurements i. -Silicon Photodiodes for absorbance measurements ii. -4-LED’s for Excitation for FP (FluorescencePolarization) measurements iii. Photon Counting Photomultiplier Tube (PMT) for luminescence iv. High Energy Xenon Flash Lamp selectable for high speed or high sensitivity J. Measurement Speed: 11 sec 96well plate, 15 sec 384 well plate, 23 sec 1536 well plate <7 sec kinetic repeat CCR: Vendors must be registered in the Central Contractor Register (CCR) prior to the award of a contract. You may register by going to www.ccr.gov. You will need your Dun & Bradstreet number and banking information. QUESTIONS DEADLINE: All questions are to be submitted via email to [email protected] no later than August 25, 2009 at 4:30 PM EST. Telephone calls will not be accepted. QUOTATIONS DUE: All quotations are due, via email to: [email protected] , no later than 4:30 PM EST on August 28, 2009. PROVISIONS and CLAUSES: The provision at FAR 52.212-1, Instructions to Offerors Commercial Items applies to this solicitation. The following agenda has been attached to this provision: None. Offerors shall include a completed copy of the provision at FAR 52.212-3, Offeror Representations and Certifications Commercial Items. The clause at FAR 52.212-4, Contract Terms and Conditions, Commercial Items applies to this acquisition. The following agenda has been attached to the clause: None. The clause at FAR 52.212-5 Contract Terms and Conditions Required to Implement Statues or Executive Orders, Commercial Items applies to this acquisition. The following FAR clauses cited are applicable: FAR 52.217-8, FAR 52.217-9, FAR 52.222-26, FAR 52.222-35, FAR 52.222-36, and FAR 52.232-33. Clauses and provisions are incorporated by reference and apply to this acquisition.

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