The U.S. Environmental Protection Agency (EPA) intends to negotiate a sole source purchase order under Simplified Acquisition Procedures to Affymetrix GeneChip Inc., 3420 Central Expressway, Santa Clara, CA 95051 for the acquisition of (8/each) Part# 900466 - Human Genome U133 Plus 2.0 Array GC Contains 6 GC HG-U133 per box; (2/each) Part #900720 - GeneChip Hybridization wash and stain kits (30 reactions per kit; (2/each) Part# 901229 - 3'IVT Express Kit. The Affymetrix GeneChip Array and 3'IVT Express Kit are designed to be used with the existing Affymetrix Instrument System that is located at EPA. Future experiments at EPA will generate data to be compared with existing Affymeterix data sets at EPA. Consistency in platform comparison is critical to genomic scientific mission at EPA. The research application of Affymetrix Arrays requires that the chip be scanned on the Affymetrix Scanner 3000. The image is displayed on a screen connected to the scanner and analog software generates a density number for each gene, to be used in the analysis. The resource of detailed analysis is deemed critical to establishing the use of technology in our laboratories and adapting the analysis protocols to specific research applications. EPA has identified Affymetrix, Inc., the only vendor capable of satisfy the requirement. The circumstance permitting is FAR 6.302 1 only one source and no other supplies or services will satisfy agency requirements. The intent of this notice is to determine if any other source(s) exist, and therefore, no solicitation (RFQ) is available. Consequently, any response failing to provide the aforementioned data and instead choosing to merely submit a routine letter requesting a copy of the RFQ will be ignored. The information received in response to this notice will be considered solely for the purpose of determining whether or not to conduct a competitive procurement. Interested parties who can meet the above requirements may submit written capabilities/specifications no later than 4:30pm EST, May 17, 2010. Submit response to the U.S. EPA, Attn: Pamela E. Smith (MC-E105-02),RTP Procurement Operations Division, Research Triangle Park, NC 27711, by fax (919) 685-3178 or by e-mail at [email protected] . No telephone request will not be honored.

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