The National Center for Advancing Translational Sciences (NCATS) is a part of the NIH, with a mission to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. The Therapeutic Development Branch (TDB) of the NCATS requires iCell motor neuron kits on a brand-name only basis for generating electrically active cultures that will be used in microelectrode array assays for toxicity screening for the N=1 Ionis ASO collaborative project.