The Uniformed Services University of the Health Sciences (USUHS), located on the Walter Reed National Military Medical Center in Bethesda, MD intends to negotiate on a sole source basis with Harlan Laboratories Inc. for a Blanket Purchase Agreement (BPA) for three years for an estimated 13,500 CD2F1 male mice per year.

The BPA is going to be used on the following research projects:

Evaluation of Drugs as Countermeasure Agents

Synergistic Radioprotection of Gastrointestinal Tract by Gamma-Tocotrienol and Statins in the Laboratory Mouse (Mus Musculus): efficacy and mechanisms

Evaluation of Delta-Tocotrienol as a Novel Radiation Countermeasure Candidate

Pre-Clinical Development of a Bridging Therapy for Radiation Injury Using Tocopherol Succinate in Mice (Mus Musculus)

Use of Myeloid Progenitors to Attenuate Radiation Induced GI Injury in Mice (Mus Musculus)

Rapid Radiation Biodosimetry to Mitigate Exposure Scenarios

Combined Hematological and Proteomic Approach for Radiation Dose
Assessment in Triage Biodosimetry Applications

Evaluate Radiation Counter measure Efficacy Against Neutron/Gamma Mixed Field Radiation

Characterization of Intramuscularly Injectable Genistein Nanosuspension for Radiation Protection

Screening Potential Drugs for Radioprotection After Total Body Irradiation Using Laboratory Mice

In Vivo Radioprotection of 17-DMAG from Ionizing Radiation Combined with Hemorrhage

Radioprotection of Small Intestine and Lung by Inhibition of Autophagy with 17-DMAG

Sole source determination is made in accordance with:

Far Part 13.106-1 Soliciting Competition

(b) Soliciting from a single source

(1) For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available.

Harlan Laboratories Inc. is the sole source provider of this specific genetic strain (CD2F1) of male mice with the same intestinal bacteria microflora as those CD2F1 mice already in use for biomedical research in the above listed research projects. The intestinal microflora of the requested animals must be similar to that of the intestinal bacterial microflora of mice already used in the research effort. The purchase of these mice will allow for the continuation of biomedical research with this animal strain. The data derived from the use of these mice will be compared to similar and relevant data collected over 25 years. For example, responses to radiation, bacterial challenge, and treatment for radiation protection are known and are all linked to the specific genotype of the animal. Responses to the CD2F1 strain of mice, from Harlan Laboratories Inc have already been established. Continue research with CD2F1 mice will allow a strict biological and statistical comparison between the data collected with the use of these requested animals to that from previous research with CD2F1 mice from Harlan.

This is not a request for quotes and a solicitation package will not be issued. A determination by the government not to compete this proposed contract action based upon responses to this notice is solely within the discretion of the government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Responses must be electronically, via email, to [email protected] by 1:00P.M. (EST) on November 22, 2011.

Bid Protests Not Available