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The National Institute of Allergy and Infectious Diseases (NIAID) is interested in expediting the completion of development of three vaccines for biodefense: (1) Rift Valley Fever vaccine; (2) Plague vaccine; and, (3) Smallpox vaccine for persons at high-risk of complications from currently available vaccines (e.g., the immune deficient).NIAID is interested in receiving letters of interest regarding these vaccines from organizations that have candidate vaccines under clinical development. Interested organizations should submit a letter of interest that contains a detailed description of the product and summary results of pre-clinical and early clinical testing. The letter of interest along with any supporting documentation shall not exceed 10 pages. Letters of interest will be kept confidential and will help in determining the need for an RFP to support further development, testing, and licensure of these products, and in assembling a potential source list for distribution if an RFP is issued. Submit your response to Barbara Shadrick, at the address listed in this Special Notice.

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