The National Heart, Lung, and Blood Institute (NHLBI) intends to negotiate on a non-competitive basis with the Coronary Artery Risk Development in Young Adults (CARDIA) study Coordinating Center and Field Centers (Coordinating Center-University of Alabama in Birmingham; Field Centers, University of Alabama in Birmingham, University of Minnesota, Northwestern University and Kaiser Foundation Research Institute) for a five year follow-on contract for the continuation of the CARDIA study. Since the initiation of the CARDIA Study in 1983 a total of 5,115 cohort participants have been recruited, examined and followed for change in and development of coronary heart disease risk factors and development of subclinical atherosclerosis in young adults. The main goal of the study renewal is to identify risk factors for and assess racial differences in the development and progression of subclinical atherosclerosis. The statutory authority applicable to this solicitation is 41 USC 253(c)(1) as set forth in FAR 6.302.1. The incumbents have the unique capability to provide the required services to the NHLBI. See NOTE 22.

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