This announcement serves as a reissuance of the BARDA DRIVe EZ-BAA, now known as EZ-BAA-22-100-SOL-00003. This announcement hereby supersedes and replaces prior iterations of the BARDA DRIVe EZ-BAA (e.g. BAA-20-100-SOL-0002). Please reference the attached announcement and applicable amendments for specifics. Additionally, please visit https://drive.hhs.gov/. 

_______

Amendment 001:  This amendment to the EZBAA hereby opens the following research areas of interest ("AOI"). Please review the amendment for details of each AOI, including closing dates: 

AOI #15: ReDIRECT
AOI #16: Lab at Home
AOI #17: Digital MCMs
AOI #18: Host-Directed Therapeutics
AOI #19: Healing Lungs
AOI #20: DRIVe Forward
AOI #21: Vaccines on Demand
AOI #22: ReBooT
AOI #23: Host-Based Diagnostics

_____

11/8/22 - Please see Amendment 002 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003.  Under this Amendment, BARDA is:

1. Adding the the following Area of Interest (AOI):

    AOI #24:  REPAIR

2. Clarifying an adminstrative error. 

_____

11/14/22 - Please see Amendment 003 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003.  Under this Amendment, BARDA is:

1. Revising the following Area of Interest (AOI): 

    AOI #19: Healing Lungs

_____

12/15/22 - Please see Amendment 004 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003.  Under this Amendment, BARDA is:

1. Updating the closing date for the following Area of Interest (AOI): 

    AOI #21: Vaccines on Demand

______

1/11/23 - Please see Amendment 005 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is:

1. Pausing the following Area of Interest (AOI) by establishing a new closing date of February 15, 2023 at 12:00PM ET:

    AOI #15: ReDIRECT

______

2/1/23 - Please see Amendment 006 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Updating the closing date for the following Area of Interest (AOI): 

AOI #19: Healing Lungs 

2. Updating the closing date for the following Area of Interest (AOI): 

AOI #17: Digital MCMs  

3. Updating the closing date for the following Area of Interest (AOI): 

AOI #16: Lab at Home 

4. Revising the following Area of Interest (AOI): 

AOI #16: Lab at Home

______

2/3/23 - Please see Amendment 007 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Updating the closing date for the following Area of Interest (AOI): 

AOI #24: REPAIR

______

5/1/23 - Please see Amendment 008 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Adding the following Area of Interest (AOI): 

AOI #25: FASTx

2. Updating the language in Section III (F) of the Easy Broad Agency Announcement titled “Plus (+) Phase”.

______

5/18/23 - Please see Amendment 009 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Reopening the following Area of Interest (AOI), which is reopened to support project Next Gen: 

AOI #21: Vaccines on Demand

______

5/25/23 - Please see Amendment 010 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Revising the following Area of Interest (AOI): 

AOI #24: REPAIR

2. Updating the closing date for the following Area of Interest (AOI): 

AOI #24: REPAIR

______

6/27/23 - Please see Amendment 011 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Closing the following Area of Interest (AOI): 

AOI #18: Host-Directed Therapeutics 

2. Closing the following Area of Interest (AOI): 

AOI #23: Host-Based Diagnostics

3. Updating the closing date for the following Area of Interest (AOI): 

AOI #19: Healing Lungs

______

9/13/23 - Please see Amendment 012 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Updating the closing date for the following Area of Interest (AOI): 

AOI #16: Lab at Home

2. Updating the closing date for the following Area of Interest (AOI): 

AOI #17: Digital MCMs

3. Updating the closing date for the following Area of Interest (AOI): 

AOI #19: Healing Lungs

4. Revising the following Area of Interest (AOI): 

AOI #16 Lab at Home

5. Adding the following Area of Interest (AOI): 

AOI #26: Agnostic Diagnostic 

_______

9/14/23 - Please see Amendment 013 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Pausing the following Area of Interest (AOI): 

AOI #20: DRIVe Forward

________

9/26/23 - Please see Amendment 014 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Pausing the following Area of Interest (AOI): 

AOI #21: Vaccines on Demand

_________

10/26/23 - Please see Amendment 015 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Updating the closing date for the following Area of Interest (AOI): 

AOI #22: ReBoot

2. Updating the closing date for the following Area of Interest (AOI): 

AOI #25: FASTx

3. Revising the following Area of Interest (AOI): 

AOI #22: ReBoot

4. Revising the following Area of Interest (AOI): 

AOI #25: FASTx

___________

10/30/23 - Please see Amendment 016 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Pausing the following Area of Interest (AOI): 

AOI #24: REPAIR

__________

11/15/23 - Please see Amendment 017 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Reopening the following Area of Interest (AOI): 

AOI #20: DRIVe Forward 

2. Revising the following Area of Interest (AOI): 

AOI #20: DRIVe Forward 

__________

12/13/23 - Please see Amendment 018 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Updating the closing date for the following Area of Interest (AOI): 

AOI #16: Lab at Home

2. Revising the following Area of Interest (AOI): 

AOI #16: Lab at Home

3. Pausing the following Area of Interest (AOI): 

AOI #17: Digital MCMs

4. Updating the closing date for the following Area of Interest (AOI): 

AOI #19: Healing Lungs

__________

01/03/24 - Please see Amendment 019 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Reopening the following Area of Interest (AOI): 

AOI #15: ReDIRECT

2. Revising the following Area of Interest (AOI): 

AOI #15: ReDIRECT

__________

01/10/24 - Please see Amendment 020 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Pausing the following Area of Interest (AOI): 

AOI #26: Agnostic Diagnostic

2. Adding a topic to the following Area of Interest (AOI): 

AOI #20: DRIVe Forward

3. Updating the closing date for the following Area of Interest (AOI):

AOI #20: DRIVe Forward

_________

01/18/24 - Please see Amendment 021 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Adding the following Area of Interest (AOI): 

AOI #27: Stopping Secondary Spread

__________

2/5/24 - Please see Amendment 022 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003.  Under this Amendment, BARDA is:

1. Pausing the following research Area of Interest (AOI):

AOI #27: Stopping Secondary Spread

2. Revise topics for the following research Area of Interest (AOI):

AOI #20: DRIVe Forward

__________

02/12/24 - Please see Amendment 023 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Reopening the following Area of Interest (AOI): 

AOI #26: Agnostic Diagnostic

__________

02/21/24 - Please see Amendment 024 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Updating the closing date for the following Area of Interest (AOI): 

AOI #22: ReBooT

2. Updating the closing date for the following Area of Interest (AOI): 

AOI #25: FASTx

__________

03/04/24 - Please see Amendment 025 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Reopening the following Area of Interest (AOI): 

AOI #24: RePAIR

2. Revising the following Area of Interest (AOI): 

AOI #24: RePAIR

__________

03/12/24 - Please see Amendment 026 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Updating the closing date for the following Area of Interest (AOI): 

AOI #16: Lab at Home

2. Updating the closing date for the following Area of Interest (AOI): 

AOI #19: Healing Lungs

_________

04/22/24 - Please see Amendment 027 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Reopening the following Area of Interest (AOI): 

AOI #20: DRIVe Forward

2. Removing two topic areas and adding one topic area to the following Area of Interest (AOI): 

AOI #20: DRIVe Forward

_________

05/01/24 - Please see Amendment 028 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Updating the closing date for the following Area of Interest (AOI): 

AOI #15: ReDIRECT

2. Updating the closing date for the following Area of Interest (AOI): 

AOI #26: Agnostic Diagnostic

3. Reopening the following Area of Interest (AOI): 

AOI #17: Digital MCMs

4. Revising the following Area of Interest (AOI):

AOI #17: Digital MCMs

__________

05/09/24 - Please see Amendment 029 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Pausing the following Area of Interest (AOI):

AOI #16: Lab at Home

2. Updating the closing date for the following Area of Interest (AOI):

AOI #19: Healing Lungs

3. Revising the following Area of Interest (AOI):

AOI #19: Healing Lungs

4. Updating the closing date for the following Area of Interest (AOI): 

AOI #24: RePAIR

_________

09/24/24 - Please see Amendment 030 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Adding the following Area of Interest (AOI):

AOI #28: Influenza Vaccine Innovation

2. Pausing the following Area of Interest (AOI):

AOI #26: Agnostic Diagnostic 

___________

09/30/24 - Please see Amendment 031 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Reopening the following Area of Interest (AOI):

AOI #24: RePAIR

___________

10/10/24 - Please see Amendment 032 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 

1. Update the closing date for the following Area of Interest (AOI): AOI #19: Healing Lungs
    
2. Pause the following Area of Interest (AOI) on 10/31/24: AOI #17: Digital MCMs

___________

10/31/24 - Please see Amendment 033 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is:

1. Reopen the following Area of Interest (AOI) on 11/1/24:

       AOI #15: ReDIRECT

       2. Remove language requiring a Rough Order of Magnitude (ROM) from the record